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Rabbit Anti-Mouse Centromere Protein H (CENPH) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse centromere protein H. It is purified by protein A/G. It can be applied to WB and IHC assays of mouse centromere protein H.
Specifications
Target Information
Mouse centromere protein H (CENP-H) is a 333-residue constitutive component of the inner kinetochore plate, spanning residues 1-40 for centromere targeting and 90-270 for CENP-C interaction. The protein adopts a predominantly α-helical fold, forms a stable heterotetramer with CENP-I/K/M/N, and localizes to active centromeres throughout the cell cycle. Constitutively expressed in dividing tissues, CENP-H is essential for kinetochore assembly and microtubule attachment. Antibodies raised against full-length or N-terminal peptide detect native CENP-H with negligible cross-reactivity to other CENP proteins, enabling precise immunoblot and immunofluorescence in mouse tissue homogenates and cultured cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.