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Rabbit Anti-Rat Regenerating Islet Derived Protein 3 Beta (REG3b) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat regenerating islet derived protein 3 beta. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat regenerating islet derived protein 3 beta.
Specifications
Target Information
Rat regenerating islet-derived protein 3 beta (Reg3b) is a 175-residue secreted C-type lectin bearing an N-terminal signal peptide, a conserved carbohydrate-recognition domain that coordinates Ca²⁺ through two extended loops, and a short hydrophobic tail. The mature polypeptide forms disulfide-linked dimers and higher-order fibrils via intermolecular cysteine bridges, yielding a 16 kDa monomer and 32 kDa dimer under reducing and non-reducing conditions, respectively. Constitutively expressed in pancreatic acinar cells and up-regulated in intestinal crypts, Reg3b localizes to the luminal surface of mucosal epithelium. Antibodies raised against recombinant rat Reg3b detect native dimers and monomers with negligible cross-reactivity to Reg3a or Reg3g, enabling precise immunoblot and immunohistochemical detection in rat tissue homogenates and sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.