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Mouse Topoisomerase II (TOP2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Topoisomerase II (TOP2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TOP2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
DNA topoisomerase 2-alpha is a crucial decatenating enzyme that modifies DNA topology by binding to two double-stranded DNA molecules, creating a double-stranded break in one of them, passing the intact strand through the break, and then religating the broken strand. In mice, TOP2A is vital for various biological processes, particularly in the onset, progression, and treatment of cancer. It has significant functions in mouse prostate cancer models; studies indicate that TOP2A is pivotal in the metastasis and progression of prostate cancer in mice. Research using a mouse transplant model has demonstrated that TOP2A is significantly upregulated in metastatic tumors and is associated with more aggressive cancer forms.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.