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Mouse Interleukin 1 Receptor Associated Kinase 3 (IRAK3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Interleukin 1 Receptor Associated Kinase 3 (IRAK3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IRAK3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Interleukin-1 receptor-associated kinase 3 is believed to be an inactive protein kinase that modulates signaling pathways downstream of immune receptors, such as IL1R and Toll-like receptors. It functions by preventing the dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex, either through the inhibition of IRAK1 and IRAK4 phosphorylation or by stabilizing the receptor complex. In mice, this kinase is encoded by the IRAK3 gene. IRAK3 inhibits inflammatory responses in mice mainly by negatively regulating the TLR signaling pathway and plays an important role in a variety of diseases (e.g., infection, inflammation, cerebral ischemia, myocardial infarction, obesity, and neoplasia).
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.