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Mouse Growth Differentiation Factor 10 (GDF10) ELISA Kit-Sandwich

Cat. No.EK6F873

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Growth Differentiation Factor 10 (GDF10) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GDF10 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Growth Differentiation Factor 10 (GDF10).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Growth/differentiation factor 10 (GDF10) is a growth factor that plays a role in osteogenesis and adipogenesis. It inhibits osteoblast differentiation through the SMAD2/3 pathway and also suppresses adipogenesis. In a mouse model of stroke, GDF10 has been shown to support axon growth and facilitate functional recovery. Studies indicate that GDF10 enhances axon growth in cortical neurons and improves motor recovery via the TGFβ receptor signaling pathway. Overexpression of GDF10 significantly boosts motor coordination and performance in grid walking tests in mice, whereas reducing GDF10 levels hampers these recovery processes. Additionally, GDF10 aids functional recovery post-stroke by promoting angiogenesis and astrogliosis.

Target/Biomarker Mouse GDF10
Target Synonym BMP-3b; BMP3B;bone morphogenetic protein 3B;BIP;
Gene ID 14560
UniProt ID P97737

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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