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Mouse Fibroblast Growth Factor 12 (FGF12) ELISA Kit-Sandwich

Cat. No.EK6F152

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Fibroblast Growth Factor 12 (FGF12) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse FGF12 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Fibroblast Growth Factor 12 (FGF12).
Target Species Mouse
Species Reactivity Mouse
Detection Range 15.7-1000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Fibroblast growth factor 12 (FGF12) plays a critical role in the development and function of the nervous system. It enhances neuronal excitability by increasing the voltage dependence of the fast inactivation of the neuronal sodium channel SCN8A. In mice, FGF12 serves several key functions, including regulation of hair growth, maintenance of hearing and balance in the inner ear, and contribution to nervous system development. The FGF12 gene is crucial for hair growth in mice. Experiments using siRNA technology to reduce FGF12 expression levels demonstrated a significant decrease in hair weight, a reduction in the number of hair follicles, and shortened hair length, underscoring the essential role of FGF12 in maintaining normal hair growth.

Target/Biomarker Mouse FGF12
Target Synonym FGF12B; FHF1; Fibroblast Growth Factor Homologous Factor 1; Myocyte-Activating Factor
Gene ID 14167
UniProt ID P61329

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Woo, Jiwon et al. "Hair Growth Regulation by Fibroblast Growth Factor 12 (FGF12)." International journal of molecular sciences vol. 23,16 9467. 22 Aug. 2022.
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