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Mouse Branched-Chain-Amino-Acid Aminotransferase, Cytosolic (BCAT1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Branched-Chain-Amino-Acid Aminotransferase, Cytosolic (BCAT1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse BCAT1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The cytosolic branched-chain-amino-acid aminotransferase catalyzes the initial step in the breakdown of the essential branched-chain amino acids leucine, isoleucine, and valine. BCAT1 plays a crucial role in metabolic reprogramming in mouse macrophages and has a strong connection to inflammatory diseases. By inhibiting BCAT1 activity, the expression of genes related to oxidative stress and inflammation in macrophages can be diminished, leading to a reduced inflammatory response. In mice, inhibiting BCAT1 can significantly suppress the production of IRG1 and succinate using ERG240 (a leucine analog), thereby mitigating the inflammatory response.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.