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Mouse Solute Carrier Family 39, Member 4 (SLC39A4) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Solute Carrier Family 39, Member 4 (SLC39A4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SLC39A4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Zinc transporter ZIP4 is encoded by the Slc39a4 gene in mice and functions as a selective transporter that facilitates the uptake of Zn2+. It is crucial for absorbing dietary zinc from the small intestine. The Zn2+ uniporter activity is regulated by the availability of zinc. Additionally, it can bind and transport Cu2+, Cd2+, and potentially Ni2+, albeit at higher concentrations. In some cancer models, SLC39A4 expression is associated with tumor progression and metastasis. For example, in a mouse model of non-small cell lung cancer, ZIP4 knockout can inhibit tumor growth and metastasis. In addition, overexpression of SLC39A4 in gallbladder cancer cells promotes cell proliferation and migration.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.