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Mouse Cytochrome P450 27B1 (CYP27B1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Cytochrome P450 27B1 (CYP27B1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CYP27B1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Cyp27b1 is a cytochrome P450 monooxygenase that plays a crucial role in vitamin D metabolism and the regulation of calcium and phosphorus levels. It facilitates the rate-limiting step in vitamin D activation within the kidney by hydroxylating 25-hydroxyvitamin D3 (calcidiol) at the C1-alpha position, thereby producing 1alpha,25-dihydroxyvitamin D3 (calcitriol), the hormonally active form of vitamin D3. This active form functions through the vitamin D receptor (VDR). In mice, Cyp27b1 is essential for the conversion of 25(OH)D3 to 1,25(OH)2D3, primarily in the kidney, influencing mineral balance and bone health. Additionally, it plays a role in modulating inflammatory responses and other pathological conditions.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.