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Mouse Chordin Like Protein 2 (CHRDL2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Chordin Like Protein 2 (CHRDL2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CHRDL2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Chordin-like protein 2 is involved in tumor angiogenesis and may inhibit BMPs activity by preventing their interaction with receptors. It acts as a negative regulator of cartilage formation and regeneration from immature mesenchymal cells by reducing matrix accumulation. In mice, the functions of CHRDL2 are complex and multifaceted, involving the protection of vascular endothelial cells and playing a significant role in cancer development and progression. CHRDL2 expression is significantly downregulated during glucocorticoid (GC)-induced injury in bone marrow endothelial cells (BMECs). However, overexpression of CHRDL2 can partially counteract the inhibitory effects of GCs on BMECs, improving cell viability, reducing apoptosis, and enhancing tubular structure formation and migration ability.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.