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Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ANGPTL3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Angiopoietin-related protein 3 functions partly as a hepatokine involved in the regulation of lipid and glucose metabolism. It is believed to facilitate the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. Angptl3 indirectly influences insulin sensitivity by modulating fatty acid metabolism. Research indicates that mice lacking Angptl3 exhibit increased insulin sensitivity, possibly due to reduced liver lipogenesis and enhanced fatty acid oxidation. In KK/A mice, a model for obesity and diabetes, knocking out or inhibiting the Angptl3 gene can significantly lower plasma triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) levels while improving insulin sensitivity.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Christopoulou, Eliza et al. "Effects of Angiopoietin-Like 3 on Triglyceride Regulation, Glucose Homeostasis, and Diabetes." Disease markers vol. 2019 6578327. 3 Mar. 2019.