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Mouse Actin-Like Protein 6B (Actl6B) ELISA Kit-Sandwich

Name: Mouse Actin-Like Protein 6B (Actl6B) ELISA Kit-Sandwich
SKU: EK6F944
Rating: 5 (1 reviews)

Cat. No.EK6F944

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Mouse Actin-Like Protein 6B (Actl6B) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse Actl6B in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Mouse Actin-Like Protein 6B (Actl6B).

Target Species Mouse

Species Reactivity Mouse

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%

Assay Time Around 90 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Actin-like protein 6B plays a role in the transcriptional activation and repression of specific genes through chromatin remodeling. It is a part of the SWI/SNF chromatin remodeling complexes, which perform essential enzymatic functions by modifying chromatin structure via altering DNA-histone interactions within a nucleosome in an ATP-dependent manner. Mice lacking ACTL6B show behavioral deficits associated with autism, such as social behavior disorders, memory issues, and repetitive actions. Furthermore, the connectivity between the hippocampus and cortex in ACTL6B knockout mice is compromised, highlighting the vital role of ACTL6B in maintaining neuronal connectivity.

Target/Biomarker Mouse Actl6B

Target Synonym Actin-Like Protein 6B; Actl6b; Actl6; Arpna; Baf53b; 53 kDa BRG1-associated factor B; Actin-related protein Baf53b; ArpN-alpha (ArpNa); BRG1-associated factor 53B (BAF53B)

Gene ID 83766

UniProt ID Q99MR0

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Han, Xiaodi et al. "Developmental and Epileptic Encephalopathy 76: Case Report and Review of Literature." Children (Basel, Switzerland) vol. 9,12 1967. 15 Dec. 2022.