This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Mouse Hemojuvelin (Hjv), N-His-GST
Product Overview
BioVenic's Recombinant Mouse Hemojuvelin (Hjv), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 68.6 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Hemojuvelin (Hjv) is a crucial protein involved in regulating systemic iron homeostasis. It acts as a bone morphogenetic protein (BMP) co-receptor and is essential for the expression of hepcidin, a hormone that controls iron absorption and release. Mutations in the Hjv gene lead to severe iron overload due to reduced hepcidin levels. In mouse models, Hjv deficiency results in iron overload and decreased hepcidin expression, highlighting its role in dietary iron sensing. Additionally, Hjv is implicated in the innate immune response to bacterial infections, suggesting its involvement in immune regulation.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.