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Recombinant Mouse Dystrophin (Dmd), N-His
Product Overview
BioVenic's Recombinant Mouse Dystrophin (Dmd), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 30.8 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Dystrophin (Dmd) is a critical protein that provides structural support to muscle fibers and is essential for maintaining muscle integrity. It is a component of the dystrophin-glycoprotein complex (DGC), which links the cytoskeleton to the extracellular matrix. Dystrophin acts as a shock absorber, protecting muscle cells from mechanical stress during contraction. In mouse models, mutations in the Dmd gene lead to Duchenne muscular dystrophy (DMD), a severe muscle-wasting disease characterized by progressive muscle weakness and degeneration. Additionally, Dystrophin plays a role in neuronal function and has been implicated in cognitive deficits associated with DMD.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in ddH2O to a concentration of 0.1-0.2 mg/mL. Do not vortex. Aliquot the reconstituted solution to minimize freeze-thaw cycles.