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Recombinant Mouse Tryptase (Tpsab1), N-His

Cat. No.AP4C741

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Tryptase (Tpsab1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 15.0 kDa. The purity is> 90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 90%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 15.0 kDa
Physical State Lyophilized
Formulation 20 mM Tris, 150 mM NaCl, pH8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Mouse Tryptase (Tpsab1) is a serine protease predominantly found in mast cells, where it is stored in secretory granules. It is involved in various physiological processes, including immune responses and inflammation. Tpsab1 is essential for the degranulation of mast cells, which is crucial for the release of histamine and other inflammatory mediators. This process is particularly important in allergic reactions, where Tpsab1 contributes to the symptoms of anaphylaxis. In addition, Tpsab1 has been shown to play a role in the regulation of gene expression in mast cells, with its expression being coordinated by transcription factors such as GATA1 and GATA2.

Protein Mouse Tryptase (Tpsab1)
Protein Synonym Mast cell protease 7; mMCP-7; Tryptase alpha/beta-1
EC No. Q02844

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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