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Recombinant Mouse Diamine Oxidase (Aoc1), N-His

Cat. No.AP4C284

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Diamine Oxidase (Aoc1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 19.8 kDa. The purity is> 95%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 95%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 19.8 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Mouse Diamine Oxidase (Aoc1) is a copper-containing amine oxidase that catalyzes the deamination of histamine and putrescine. It plays roles in lipid metabolism, with studies showing that Aoc1 deficiency in mice leads to increased fat mass and impaired glucose tolerance under high-fat diets. Aoc1 is also implicated in cancer progression, where its expression is elevated in certain cancer cells, promoting tumor growth and metastasis. Additionally, Aoc1 is involved in immune responses and inflammation. Its functions make it a potential therapeutic target in metabolic disorders and cancer.

Protein Mouse Diamine Oxidase (Aoc1)
Protein Synonym Diamine oxidase; Amine oxidase copper domain-containing protein 1; Histaminase
Gene ID 76507
EC No. Q8JZQ5

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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