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Recombinant Mouse Complement C3 (C3), N-His
Product Overview
BioVenic's Recombinant Mouse Complement C3 (C3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 41.6 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Complement C3 (C3) is a central component of the complement system, which is part of the innate immune response. It is synthesized in the liver and circulates in the plasma as an inactive precursor. Upon activation, C3 is cleaved into C3a and C3b, which play distinct roles in immune defense. C3b opsonizes pathogens and debris for phagocytosis, while C3a acts as an anaphylatoxin, inducing inflammation and attracting immune cells. C3 is involved in the clearance of immune complexes and apoptotic cells. Dysregulation of C3 has been implicated in various immune-mediated diseases, including autoimmune conditions and infections.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-0.5 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.