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Recombinant Mouse Bactericidal Permeability-Increasing Protein (Bpi), N-His

Cat. No.AP4C759

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Bactericidal Permeability-Increasing Protein (Bpi), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 19.1 kDa. The purity is> 97%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 97%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 19.1 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Mouse Bactericidal Permeability-Increasing Protein (Bpi) is a key component of the immune system, primarily found in neutrophils. It plays a crucial role in host defense against gram-negative bacteria by binding to lipopolysaccharides (LPS) on the bacterial surface, leading to increased membrane permeability and bacterial death. Bpi is also involved in the regulation of immune responses, including the activation of the NF-κB pathway and the production of pro-inflammatory cytokines. In mouse models, Bpi deficiency results in increased susceptibility to bacterial infections, highlighting its importance in innate immunity.

Protein Mouse Bactericidal Permeability-Increasing Protein (Bpi)
Protein Synonym BPI; Bpi
Gene ID 329547
EC No. Q67E05

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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