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Recombinant Mouse Semaphorin-7A (Sema7a), N-His
Product Overview
BioVenic's Recombinant Mouse Semaphorin-7A (Sema7a), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 32.0kD. The purity is> 95%.
Specifications
Target Information
Mouse Semaphorin-7A (Sema7a) is a member of the semaphorin family of proteins, which are involved in various biological processes, including axon guidance, immune responses, and cell migration. Sema7a is a transmembrane protein that interacts with Plexin C1 and the β1-integrin receptor to mediate cell-cell and cell-matrix interactions. In the immune system, Sema7a plays a crucial role in the regulation of T cell activation and dendritic cell function. It also promotes the survival and proliferation of T cells by enhancing the PI3K/Akt signaling pathway. In mouse models, Sema7a has been implicated in the regulation of immune responses and inflammation, with its expression being upregulated in conditions such as sepsis and endotoxemia.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.