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Recombinant Swine Complement C3 (C3), N-His
Product Overview
BioVenic's Recombinant Swine Complement C3 (C3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 34.8 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Swine complement C3 (C3) is a pivotal component of the complement system, involved in the convergence of the classical, alternative, and lectin activation pathways, playing a crucial role in bacteriolysis, inflammation, opsonization, and immune regulation . In swine, research on C3 helps to understand its role in energy metabolism and disease, providing a basis for developing new therapeutic strategies . For example, CRISPR/Cas9-mediated knockout of the C3 gene in pigs has shown that these piglets have undetectable plasma C3 protein and significantly reduced hemolytic complement activity and complement-dependent cytotoxicity .
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.