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Recombinant Feline Proenkephalin-A (PENK)
Product Overview
BioVenic's Recombinant Feline Proenkephalin-A (PENK) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 21.3 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
In felines, proenkephalin-A (PENK) is a precursor protein that generates bioactive peptides like Met-enkephalin and Leu-enkephalin. These peptides bind to opioid receptors, modulating pain perception, mood, and stress responses. Additionally, PENK fragment A 119-159 (PenKid) serves as a stable biomarker for kidney function, particularly in detecting acute kidney injury (AKI) early. PENK levels in plasma correlate inversely with glomerular filtration rate (GFR), making it a potential early indicator of renal dysfunction.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.