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Recombinant Chicken Prostaglandin G/H Synthase 2 (PTGS2)
Product Overview
BioVenic's Recombinant Chicken Prostaglandin G/H Synthase 2 (PTGS2) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 69.1 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Chicken Prostaglandin G/H Synthase 2 (PTGS2), also known as cyclooxygenase-2 (COX-2), is a key enzyme involved in the synthesis of prostaglandins, which are lipid compounds that play crucial roles in inflammation, pain, and fever regulation. PTGS2 catalyzes the conversion of arachidonic acid to prostaglandin H2 (PGH2), a precursor for various prostaglandins and thromboxanes. In chickens, PTGS2 is expressed in various tissues and is particularly important in the inflammatory response and reproductive processes. It is also involved in the regulation of luteolysis, a process critical for the maintenance of the reproductive cycle. Additionally, PTGS2 has been implicated in the regulation of cell proliferation and apoptosis, making it a potential target for therapeutic interventions in inflammatory and reproductive disorders.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.