This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Chicken Gap Junction Alpha-3 Protein (GJA3)
Product Overview
BioVenic's Recombinant Chicken Gap Junction Alpha-3 Protein (GJA3) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 55.8 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Chicken Gap Junction Alpha-3 Protein (GJA3), also known as connexin 46 (Cx46), is a key component of gap junctions, which are specialized intercellular connections that facilitate direct communication between cells. GJA3 is highly conserved across species and is essential for maintaining ionic and water balance, as well as the transparency and optical properties of the lens in the eye. Defects in the GJA3 gene are associated with congenital cataracts, a condition characterized by clouding of the lens that can impair vision. In chickens, GJA3 plays a crucial role in lens development and function, ensuring proper cellular communication and tissue integrity. Abnormal expression or mutations in GJA3 can lead to disruptions in these processes, resulting in developmental abnormalities and diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.