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Recombinant Chicken Alpha-Actinin-1 (ACTN1)

Cat. No.AP1C387

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Chicken Alpha-Actinin-1 (ACTN1) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 103.2 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Chicken
Expression System E.coli
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 103.2 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Target Information

Chicken alpha-actinin-1 (ACTN1) is an actin-binding protein belonging to the spectrin gene superfamily, primarily expressed in non-muscle cells. It plays a crucial role in the cytoskeleton, participating in cell proliferation, migration, and adhesion. In chickens, ACTN1 is expressed in various cell types, including endothelial and smooth muscle cells. Studies show that ACTN1 is involved in embryonic development and tissue repair in chickens, regulating the stability of the cytoskeleton and cell connections to promote cell movement and proliferation. Additionally, ACTN1 plays a role in the immune system, particularly in response to pathogen infection, by regulating cell adhesion and migration to enhance immune responses. These findings indicate that ACTN1 is crucial for growth, development, and health in chickens.

Protein Chicken Alpha-Actinin-1 (ACTN1)
Protein Synonym Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1
Gene ID 373918
UniProt ID P05094

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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