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Native Bovine Bone Osteocalcin (BGLAP)

Product Overview

BioVenic's Native Bovine Bone Osteocalcin (BGLAP) is a native protein derived from Bovine Bone.

Specifications

Type Native Protein

Species Bovine

Source Bone

Purification Affinity Purified

Purity >95% (SDS-PAGE)

Predicted Molecular Weight 11 kDa

Physical State Liquid

Formulation pH 7.40, 0.121% Tris, 50% Glycerol, 0.435% Sodium chloride.

Target Information

Bone gamma-carboxyglutamate protein, also known as osteocalcin (OCN), is encoded by the BGLAP gene in cattle. It is a small, highly conserved molecule first identified in the mineralized matrix of bone. It is primarily found in the mineralized matrix of bone, especially in association with osteoblasts, the cells responsible for bone formation. Gla residues in OCN allow it to bind effectively with calcium, contributing to the mineralization and strength of the bone matrix.

Protein Bovine Osteocalcin (BGLAP)

Protein Synonym bone gamma-carboxyglutamate protein; BGP; osteocalcin; bone Gla protein; gamma-carboxyglutamic acid-containing protein

Gene ID 281646

UniProt ID P02820

Shipping and Storage

Store at 4°C. Avoid freeze and thaw cycles.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Kayed, H. et al. BGLAP is expressed in pancreatic cancer cells and increases their growth and invasion. Molecular Cancer. 2007, 6: 83.