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Recombinant Canine T-cell Surface Glycoprotein CD4 (CD4), C-His
Product Overview
BioVenic's Recombinant Canine T-cell Surface Glycoprotein CD4 (CD4), C-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 43.0 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Canine T-cell surface glycoprotein CD4 is a crucial surface marker on T helper cells, playing a vital role in immune responses. It primarily functions as a coreceptor for the interaction between T cells and antigen-presenting cells (APCs) via the MHC class II molecule:peptide complex. This interaction is essential for T-cell activation, leading to lymphokine production, motility, adhesion, and the activation of T-helper cells. In dogs, CD4+ T cells are key in initiating and regulating adaptive immune responses, particularly in the context of antigen recognition and presentation.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute at 250 μg/mL in PBS.Aliquote the reconstituted solution to minimise freeze-thaw cycles.