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Recombinant Mouse Prelamin-A/C (Lmna), N-His
Product Overview
BioVenic's Recombinant Mouse Prelamin-A/C (Lmna), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 52.2 kDa. The purity is> 95%.
Specifications
Target Information
Mouse Prelamin-A/C (Lmna) is a gene that encodes proteins essential for maintaining nuclear structure and function. The encoded proteins, lamin A and lamin C, are components of the nuclear envelope and play crucial roles in DNA replication, transcriptional regulation, and chromatin organization. Mutations in Lmna can lead to a variety of diseases, including muscular dystrophy, cardiomyopathy, and premature aging syndromes. In mouse models, Lmna deficiency results in severe developmental defects and early lethality due to compromised nuclear integrity and impaired cellular function.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.