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Recombinant Canine Interleukin-4 Receptor Subunit Alpha (IL4R), C-His
Product Overview
BioVenic's Recombinant Canine Interleukin-4 Receptor Subunit Alpha (IL4R), C-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 24.8 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Canine IL4Rα is a critical type I transmembrane glycoprotein that serves as a common subunit for both Type I and Type II interleukin-4 receptors. It binds with high affinity to IL-4 and IL-13, triggering the JAK/STAT6 signaling pathway. In dogs, this receptor is a key regulator of Th2 cell differentiation, IgE antibody production, and allergic inflammation. It is a major therapeutic target for treating canine atopic dermatitis and other immune-mediated hypersensitivity disorders.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.