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Recombinant Swine Metalloproteinase Inhibitor 4 (TIMP4), N-His-GST
Product Overview
BioVenic's Recombinant Swine Metalloproteinase Inhibitor 4 (TIMP4), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 50.9 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Swine metalloproteinase inhibitor 4 (MMP inhibitor 4), also known as TIMP-4, is a member of the tissue inhibitors of metalloproteinases (TIMPs) family. It forms complexes with matrix metalloproteinases (MMPs), irreversibly inactivating them by binding to their catalytic zinc cofactor. TIMP-4 has inhibitory effects on a range of MMPs, particularly MMP-1, MMP-2, MMP-3, MMP-7, and MMP-9.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.