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Recombinant Canine Immunoglobulin Heavy Constant Epsilon (IgE Fc Fragment), C-His
Product Overview
BioVenic's Recombinant Canine Immunoglobulin Heavy Constant Epsilon (IgE Fc Fragment), C-His is a recombinant protein expressed from Mammalian Expression System. Its predicted molecular weight is 39.5 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
IGHE encodes the constant region of the immunoglobulin E (IgE) heavy chain in dogs. It plays a pivotal role in the canine adaptive immune response, particularly in mediating Type I hypersensitivity and defense against parasitic infections. Upon binding to high-affinity Fc epsilon RI receptors on mast cells and basophils, it triggers the release of inflammatory mediators. It is a critical target for research into canine atopic dermatitis, allergic asthma, and the development of therapeutic monoclonal antibodies.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.