Recombinant Mouse Angiopoietin-Related Protein 3 (Angptl3), C-His

Mouse Angiopoietin-Related Protein 3 (Angptl3) is a member of the angiopoietin-related protein family, which plays a significant role in lipid metabolism and vascular biology. Angptl3 is primarily produced in the liver and is secreted into the bloodstream, where it modulates the activity of lipoprotein lipase. In mice, Angptl3 has been shown to influence the metabolism of triglycerides and cholesterol, affecting the assembly and secretion of very-low-density lipoproteins. It also participates in the regulation of endothelial cell function and blood vessel integrity. Genetic studies in mice have linked variations in Angptl3 expression to plasma lipid levels and the development of atherosclerosis, making it a potential target for therapies aimed at modulating lipid metabolism and preventing cardiovascular diseases.