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Rabbit Anti-Rat Programmed Cell Death Protein 1 Ligand 1 (PDL1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat programmed cell death protein 1 ligand 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat programmed cell death protein 1 ligand 1.
Specifications
Target Information
Rat programmed cell death protein 1 ligand 1 (PD-L1, CD274) is a 32 kDa type-I transmembrane glycoprotein whose IgV-like domain and short cytoplasmic tail engage PD-1, delivering inhibitory cues to T cells. A solvent-exposed 14-aa "KVE" loop (aa 135-148) between the CC' and F strands of the IgV fold folds into a β-hairpin unique among rat B7 family members, presenting a conformational epitope preserved after glycosylation and fixation. Affinity-purified antibodies targeting this loop trace native PD-L1 in splenic dendritic cells, alveolar epithelium, and cardiac endothelium, delivering crisp membrane rings and single-band clarity on immunoblots with no cross-reaction to PD-L2 or other B7 ligands.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.