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Rabbit Anti-Rat Low Density Lipoprotein Receptor (LDLR) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat low density lipoprotein receptor. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat low density lipoprotein receptor.
Specifications
Target Information
Rat low-density lipoprotein receptor (LDLR) is a 120 kDa type-I membrane glycoprotein whose seven LA repeats and EGF precursor region fold into a pH-sensitive clamp that captures LDL particles. A solvent-exposed 14-aa "KVE" loop (aa 265-278) between LA4 and LA5 folds into a β-hairpin unique among rat LDLR family members, presenting a conformational epitope preserved after fixation. Affinity-purified antibodies targeting this loop trace native LDLR in hepatic sinusoids, adrenal cortex, and vascular endothelium, delivering crisp membrane rings and single-band clarity on immunoblots with no cross-reaction to LRP1 or VLDLR.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.