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Rabbit Anti-Rat Lipase A Lysosomal Acid (LIPA) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat lipase A lysosomal acid. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat lipase A lysosomal acid.
Specifications
Target Information
Rat Lipase A, also known as lysosomal acid lipase (LIPA), is a critical enzyme encoded by the Lipa gene. It hydrolyzes cholesteryl esters and triglycerides within lysosomes, generating free fatty acids and cholesterol. LIPA is essential for lipid metabolism and is expressed in various cell types, with its activity regulated by factors such as transcription factor EB (TFEB) and forkhead box O1 (FoxO1). Deficiencies in LIPA lead to severe lipid storage disorders, including Wolman disease and cholesterol ester storage disease.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Hayase, K., and A. L. Tappel. "Specificity and other properties of lysosomal lipase of rat liver." Journal of Biological Chemistry 245.1 (1970): 169-175.