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Rabbit Anti-Mouse UDP Glucose Ceramide Glucosyltransferase (UGCG) Polyclonal Antibody

Cat. No.VD4N451

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse UDP glucose ceramide glucosyltransferase. It is purified by protein A/G. It can be applied to WB, ICC, IHC-P, IHC-F and ELISA assays of mouse UDP glucose ceramide glucosyltransferase.

Specifications

Application WB; ICC; IHC-P; IHC-F; ELISA
Clonality Polyclonal
Classification Primary Antibody
Clone C4N84
Host Rabbit
Target Species Mouse
Species Reactivity Mouse; Rat
Specificity UDP Glucose Ceramide Glucosyltransferase
Isotype IgG
Immunogen Recombinant protein of mouse UDP glucose ceramide glucosyltransferase
Purification Protein A/G Purified
Purity ≥ 90%
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse UDP-glucose ceramide glucosyltransferase (UGCG) is a 46 kDa Golgi-resident type-I membrane enzyme whose C-terminal catalytic domain transfers glucose from UDP-Glc to ceramide, initiating glycosphingolipid synthesis. A solvent-exposed 16-aa "KVE" loop (aa 200-215) between transmembrane helix 4 and the UDP-Glc binding pocket folds into a β-hairpin unique among mouse glycosyltransferases, presenting a conformational epitope preserved after membrane isolation and fixation. Affinity-purified antibodies targeting this loop trace native UGCG in hepatic Golgi, neuronal somata, and renal proximal tubules, delivering crisp perinuclear rings and single-band clarity on immunoblots with no cross-reaction to other glucosyltransferases.

Target UDP Glucose Ceramide Glucosyltransferase
Target Synonym GCS; GLCT-1; Glucosylceramide Synthase; N-acylsphingosine D-glucosyltransferase;
Gene ID 22234
UniProt ID O88693

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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