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Rabbit Anti-Rat Glutathione S Transferase Mu 4 (GSTm4) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat glutathione S transferase mu 4. It is purified by protein A/G. It can be applied to WB and IHC assays of rat glutathione S transferase mu 4.
Specifications
Target Information
Rat glutathione S transferase mu 4 (GSTM4) is a cytosolic phase II detoxification enzyme with conserved structural domains, a core mediator of cellular antioxidant defense and xenobiotic metabolism. It features an N-terminal glutathione-binding domain, a C-terminal hydrophobic substrate-binding pocket, and a conserved active-site motif critical for catalytic conjugation reactions. It localizes predominantly to the cytoplasm of rat hepatic cells, renal tubular cells and pulmonary epithelial cells, with negligible expression in mature hematopoietic cells. The protein mediates the conjugation of glutathione to electrophilic substrates, with conserved structural motifs differentiating it from GSTM1 and other GST isoforms.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.