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Rabbit Anti-Rat Cluster of Differentiation 6 (CD6) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat cluster of differentiation 6. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat cluster of differentiation 6.
Specifications
Target Information
Rat cluster of differentiation 6 (CD6) is a 655-residue type I transmembrane glycoprotein whose extracellular region contains three scavenger-receptor cysteine-rich (SRCR) domains that bind CD166 (ALCAM). A single transmembrane helix anchors the protein to thymocytes and mature T cells, while a 44-aa cytoplasmic tail carries two tyrosine-based motifs recruiting SLP-76 and other adaptors. Constitutively expressed in spleen, thymus and lymph nodes, CD6 localizes to the immunological synapse and microvilli. Antibodies raised against SRCR3 or cytoplasmic peptide detect native, glycosylated and proteolytically shed forms with negligible cross-reactivity to CD5 or other SRCR proteins, enabling selective immunoblot and immunofluorescence analysis in rat lymphoid tissue homogenates and cultured immune cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.