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Rabbit Anti-Mouse High Mobility Group Protein 1 (HMGB1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse high mobility group protein 1. It is affinity purified by protein A. It can be applied to WB, IHC and ICC/IF assays of mouse high mobility group protein 1.
Specifications
Target Information
Mouse high mobility group protein 1 (HMGB1) is a non-histone chromatin-binding protein involved in multiple cellular processes. It stabilizes nucleosomes and facilitates transcription by remodeling chromatin structure. HMGB1 also functions as an alarmin, released by damaged cells to trigger immune responses. In the extracellular space, it acts as a pro-inflammatory cytokine, activating immune cells and promoting inflammation. HMGB1 is expressed in various tissues and is critical for maintaining genomic stability and regulating immune signaling. As a key regulator of both nuclear and cytoplasmic functions, HMGB1 is an important target for studying inflammation, tissue repair, and cancer biology.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.