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Rabbit Anti-Mouse Octamer Binding Transcription Factor 1 (OCT1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse octamer binding transcription factor 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse octamer binding transcription factor 1.
Specifications
Target Information
Mouse octamer-binding transcription factor 1 (Oct-1, Pou2f1) is a 743-residue nuclear protein containing a bipartite POU domain: a 75-aa POU-specific box and a 60-aa POU homeobox that together recognize the consensus 5'-ATGCAAAT-3'. The N-terminal transactivation region is rich in serine, proline and glutamine, while a C-terminal leucine zipper mediates dimerization. Expressed ubiquitously in all tissues, Oct-1 localizes to euchromatin and heterochromatin, regulating housekeeping and cell-type-specific genes. Antibodies raised against the POU domain or N-terminal epitope detect native, phosphorylated and alternatively spliced isoforms with negligible cross-reactivity to Oct-2 or other POU factors, enabling selective immunoblot, immunohistochemistry and chromatin immunoprecipitation in mouse tissue homogenates and cultured cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.