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Rabbit Anti-Mouse Caspase 1 (CASP1) Polyclonal Antibody

Cat. No.VD3N45

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse caspase 1. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse caspase 1.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N543
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Caspase 1
Isotype IgG
Immunogen Recombinant protein of mouse caspase 1
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Caspase 1 is an inflammatory cysteine protease that cleaves pro-IL-1β and pro-IL-18 into active cytokines. It forms the inflammasome complex, triggering pyroptosis and amplifying innate immune responses. Expressed in macrophages, dendritic cells, and epithelial tissues, it is essential for host defense and stress signaling. As a key regulator of inflammation, Caspase 1 is a valuable target for investigating immune activation and pyroptotic pathways.

Target Mouse Caspase 1
Target Synonym ICE; IL1BC; IL1-BC; P45; Interleukin 1 Beta Converting Enzyme; Apoptosis-Related Cysteine Peptidase; Interleukin-1 beta convertase
Gene ID 12362
UniProt ID P29452

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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