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Rabbit Anti-Bovine Prolactin Receptor (PRLR) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine prolactin receptor. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of bovine prolactin receptor.
Specifications
Target Information
Bovine prolactin receptor (PRLR) is a transmembrane glycoprotein encoded by the PRLR gene in Bos taurus, mapped to chromosome 20. It belongs to the cytokine receptor superfamily, featuring an extracellular ligand-binding domain with conserved cytokine receptor homology regions, a single transmembrane segment and an intracellular signaling domain. It localizes to cell membrane, with tissue-specific expression in bovine mammary gland, ovary, uterus and liver, with low levels in skeletal muscle and adipose tissues. PRLR mediates intracellular signal transduction upon ligand binding, with conserved structural motifs critical for dimerization and activation. Bovine PRLR shares high homology with mammalian orthologs, and has distinct ligand-binding affinity that differentiates it from other cytokine receptor family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.