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Rabbit Anti-Bovine Interleukin 1 Beta (IL1b) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine interleukin 1 beta. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of bovine interleukin 1 beta.
Specifications
Target Information
Bovine interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine encoded by the IL1B gene in Bos taurus, mapped to chromosome 23. It belongs to the interleukin 1 family, synthesized as an inactive pro-peptide requiring cleavage for activation, with a mature molecular weight of approximately 17 kDa. It localizes to cytoplasm and extracellular matrix, predominantly expressed in bovine monocytes, macrophages and activated neutrophils, with restricted distribution in spleen and lymphoid tissues. It harbors a conserved IL-1 family signature motif and lacks a signal peptide for classical secretion. Bovine IL-1β shares conserved functional domains with mammalian orthologs, with distinct amino acid residues differentiating it from IL-1α and other family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.