Get a quote

We're excited to learn more about your project and provide you with a customized quote tailored to your needs. Please fill out the form below, and we'll get back to you as soon as possible.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Mouse Tyrosine-protein Kinase Receptor Tie-1 (Tie1) ELISA Kit-Sandwich

Cat. No.EK5F460

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Tyrosine-protein Kinase Receptor Tie-1 (Tie1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse Tie1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Tyrosine-protein Kinase Receptor Tie-1 (Tie1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.63-40 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Tyrosine-protein kinase receptor Tie-1 is a transmembrane tyrosine-protein kinase that may influence TEK/TIE2 activity and play a role in regulating angiogenesis. In mice, Tie-1 primarily functions in vascular development, endothelial cell survival, and vascular stability. It is crucial for maintaining the integrity and survival of endothelial cells during embryonic development. Research indicates that Tie-1 gene knockout mouse embryos experience severe edema and microvascular rupture between 13.5 to 14.5 days of gestation, leading to death at 14.5 days. This demonstrates that Tie-1 is vital during vascular development, particularly in the angiogenesis stage of capillaries.

Target/Biomarker Mouse Tie1
Target Synonym JTK14; Tyrosine Kinase With Immunoglobulin And Epidermal Growth Factor Homology Domains 1; Tyrosine-protein kinase receptor Tie-1
Gene ID 21846
UniProt ID Q06806

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

Inquiry Basket