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Mouse Phenylalanine Hydroxylase (PAH) ELISA Kit-Sandwich

Cat. No.EK6F607

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Phenylalanine Hydroxylase (PAH) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PAH in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Phenylalanine Hydroxylase (PAH).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Phenylalanine-4-hydroxylase is an enzyme responsible for the hydroxylation of L-phenylalanine to L-tyrosine. In mice, its primary function involves metabolizing phenylalanine into tyrosine, a process that occurs mainly in the liver and kidneys and is crucial for the overall metabolism of phenylalanine. The activity of phenylalanine-4-hydroxylase is closely linked to metabolic disorders such as phenylketonuria (PKU). PKU results from inadequate activity of this enzyme, leading to the accumulation of phenylalanine due to its improper conversion to tyrosine. Additionally, chronic immune stimulation can impair the enzyme's activity, thereby affecting tyrosine production.

Target/Biomarker Mouse PAH
Target Synonym PKU; PKU1; Phe-4-monooxygenase
Gene ID 18478
UniProt ID P16331

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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