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Mouse Metallothionein 2 (MT2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Metallothionein 2 (MT2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse MT2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Metallothioneins are rich in cysteine residues, enabling them to bind various heavy metals. The expression of these proteins is regulated at the transcriptional level by both heavy metals and glucocorticoids. In mice, MT2 performs a broad array of biological functions, including anti-oxidative stress, neuroprotection, immunomodulation, disease treatment, and the regulation of metal ion homeostasis. MT2 is notably expressed in the mouse brain, where it helps reduce oxidative stress by binding metal ions like zinc. In mouse models of ALS (amyotrophic lateral sclerosis), a reduction in MT2 expression is linked to increased mechanical sensitivity and motor dysfunction.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Huang, Xuelin et al. "Downregulation of metallothionein-2 contributes to oxaliplatin-induced neuropathic pain." Journal of neuroinflammation vol. 18,1 91. 13 Apr. 2021.