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Mouse Glucose 6 Phosphate Isomerase (GPI) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Glucose 6 Phosphate Isomerase (GPI) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GPI in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
In the cytoplasm, Glucose-6-phosphate isomerase converts glucose-6-phosphate to fructose-6-phosphate, marking the second step of glycolysis, and performs the reverse reaction during gluconeogenesis. Beyond its role as a glycolytic enzyme, it functions as a secreted cytokine and angiogenic factor (AMF) that stimulates endothelial cell motility. This dimeric enzyme catalyzes the interconversion between D-glucose-6-phosphate and D-fructose-6-phosphate, playing a crucial role in cellular metabolism, particularly in glycolysis. Deleting the GPI gene in mice results in embryonic lethality, as studies indicate that mouse embryos lacking GPI function are unable to develop normally, underscoring the enzyme's importance in organismal development.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.