Mouse Glucagon Like Peptide 2 (GLP2) ELISA Kit-Competitive

GLP-2 is an intestinal growth factor produced by enteroendocrine L cells that significantly promotes the growth and proliferation of the small intestine. Research has demonstrated that GLP-2 significantly boosts the height and weight of small intestinal villi by stimulating crypt cell proliferation and reducing apoptosis in intestinal epithelial cells. Additionally, GLP-2 can counteract intestinal atrophy caused by total parenteral nutrition and further promote intestinal repair by activating the insulin-like growth factor-1 (IGF-1) signaling pathway. In mouse models of obesity and high-fat diets, GLP-2 has been shown to enhance glucose homeostasis and lipid metabolism, improving glucose tolerance and insulin sensitivity in obese mice. Furthermore, GLP-2 alleviates symptoms of colitis and ulcerative colitis by inhibiting inflammatory pathways like NF-κB and IL-6. It also possesses anti-inflammatory properties, helping to mitigate radiation-induced intestinal damage and promoting intestinal function recovery.