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Mouse Ribosomal Protein S6 Kinase Alpha 3 (RPS6KA3) ELISA Kit-Sandwich

Name: Mouse Ribosomal Protein S6 Kinase Alpha 3 (RPS6KA3) ELISA Kit-Sandwich
SKU: EK5F71
Rating: 5 (1 reviews)

Cat. No.EK5F71

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Mouse Ribosomal Protein S6 Kinase Alpha 3 (RPS6KA3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse RPS6KA3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Mouse Ribosomal Protein S6 Kinase Alpha 3 (RPS6KA3).

Target Species Mouse

Species Reactivity Mouse

Detection Range 15.7-1000 pg/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%

Assay Time Around 90 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

In mice, Ribosomal Protein S6 Kinase Alpha 3 is encoded by the Rps6ka3 gene. It is a serine/threonine-protein kinase that functions downstream of ERK signaling (MAPK1/ERK2 and MAPK3/ERK1). This kinase facilitates the activation of transcription factors CREB1, ETV1/ER81, and NR4A1/NUR77 in response to mitogenic and stress stimuli. It also regulates translation by phosphorylating RPS6 and EIF4B, and contributes to cellular processes such as proliferation, survival, and differentiation. It does so by modulating mTOR signaling and suppressing the pro-apoptotic functions of BAD and DAPK1.

Target/Biomarker Mouse RPS6KA3

Target Synonym 90 kDa ribosomal protein S6 kinase 3 (p90-RSK 3; p90RSK3) MAP kinase-activated protein kinase 1b (MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b) Ribosomal S6 kinase 2 (RSK-2) pp90RSK2

Gene ID 110651

UniProt ID P18654

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.