Mouse Galectin 3 (GAL3) ELISA Kit-Sandwich

Galectin-3 is a galactose-specific lectin that can bind to IgE and may interact with the alpha-3, beta-1 integrin to facilitate CSPG4-induced migration of endothelial cells. It is also essential, along with DMBT1, for the terminal differentiation of columnar epithelial cells during early embryogenesis. In mouse models, the functions of Galectin-3 are intricate and varied, encompassing areas such as immune regulation, inflammatory response, fibrosis, tumor development, and metabolic diseases. It plays a crucial role in the immune system; for instance, in lung infections like Klebsiella pneumoniae and Candida albicans, Galectin-3 diminishes inflammatory responses by boosting neutrophil function. In neurodegenerative diseases, Galectin-3 has been identified as a potential biomarker in spinal cord tissue and might be involved in the progression of these diseases.