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Mouse Gamma-enolase (NSE) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Gamma-enolase (NSE) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse NSE in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Gamma-enolase exhibits neurotrophic and neuroprotective properties across a wide range of central nervous system (CNS) neurons. It binds to cultured neocortical neurons in a calcium-dependent manner, promoting their survival. Eno2 is expressed in neurons and is linked to various neurodegenerative diseases. For instance, in the Ugt1 knockout mouse model, Eno2 overexpression is associated with neuronal cell death in the brain, potentially related to bilirubin-induced oxidative stress. Additionally, in a mouse model of aneurysm formation, Eno2 influences cell fate by regulating autophagy-related pathways, such as PI3K and MAPK/ERK26.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Bortolussi, G et al. "Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice." Cell death & disease vol. 6,5 e1739. 7 May. 2015.